£€0€ €0€ €0€ €?½¡€0€ €1F8B¡€remark 3: Refinement.¡€&remark 3: Program : X-Plor 3.851¡€!remark 3: Authors : Brunger¡€$remark 3: Data Used In Refinement.¡€4remark 3: Resolution Range High (Angstroms) : 1.80¡€4remark 3: Resolution Range Low (Angstroms) : Null¡€5remark 3: Data Cutoff (Sigma(F)) : 0.000¡€4remark 3: Data Cutoff High (Abs(F)) : Null¡€4remark 3: Data Cutoff Low (Abs(F)) : Null¡€4remark 3: Completeness (Working+test) (%) : Null¡€5remark 3: Number Of Reflections : 34793¡€+remark 3: Fit To Data Used In Refinement.¡€3remark 3: Cross-Validation Method : Null¡€5remark 3: Free R Value Test Set Selection : Random¡€4remark 3: R Value (Working Set) : 0.166¡€4remark 3: Free R Value : 0.214¡€3remark 3: Free R Value Test Set Size (%) : Null¡€3remark 3: Free R Value Test Set Count : 1726¡€3remark 3: Estimated Error Of Free R Value : Null¡€.remark 3: Fit In The Highest Resolution Bin.¡€6remark 3: Total Number Of Bins Used : Null¡€6remark 3: Bin Resolution Range High (A) : Null¡€6remark 3: Bin Resolution Range Low (A) : Null¡€6remark 3: Bin Completeness (Working+test) (%) : Null¡€6remark 3: Reflections In Bin (Working Set) : Null¡€6remark 3: Bin R Value (Working Set) : Null¡€6remark 3: Bin Free R Value : Null¡€6remark 3: Bin Free R Value Test Set Size (%) : Null¡€6remark 3: Bin Free R Value Test Set Count : Null¡€6remark 3: Estimated Error Of Bin Free R Value : Null¡€remark 3: Group 1 Positional (A) : Null ; Null¡€remark 200: Experiment Type : X-Ray Diffraction¡€8remark 200: Date Of Data Collection : 20-Dec-1996¡€2remark 200: Temperature (Kelvin) : 113.0¡€1remark 200: Ph : 5.90¡€.remark 200: Number Of Crystals Used : 1¡€-remark 200: Synchrotron (YN) : N¡€;remark 200: Radiation Source : Rotating Anode¡€1remark 200: Beamline : Null¡€7remark 200: X-Ray Generator Model : Macscience¡€-remark 200: Monochromatic Or Laue (ML) : M¡€3remark 200: Wavelength Or Range (A) : 1.5418¡€1remark 200: Monochromator : Null¡€1remark 200: Optics : Null¡€8remark 200: Detector Type : Image Plate¡€ FOR THE DATA SET : 10.6000¡€,remark 200: In The Highest Resolution Shell.¡€;remark 200: Highest Resolution Shell, Range High (A) : Null¡€;remark 200: Highest Resolution Shell, Range Low (A) : Null¡€1remark 200: Completeness For Shell (%) : Null¡€1remark 200: Data Redundancy In Shell : Null¡€1remark 200: R Merge For Shell (I) : Null¡€1remark 200: R Sym For Shell (I) : Null¡€0remark 200: FOR SHELL : NULL¡€3remark 200: Diffraction Protocol: Single Wavelength¡€8remark 200: Method Used To Determine The Structure: Null¡€!remark 200: Software Used: X-Plor¡€ remark 200: Starting Model: Null¡€remark 200: Remark: Null¡€remark 280: Crystal¡€+remark 280: Solvent Content, Vs (%): Null¡€9remark 280: Matthews Coefficient, Vm (Angstroms3DA): NULL¡€1remark 280: Crystallization Conditions: Phosphate¡€%remark 290: Crystallographic Symmetry¡€7remark 290: Symmetry Operators For Space Group: I 4 3 2¡€remark 290: Symop Symmetry¡€remark 290: Nnnmmm Operator¡€remark 290: 1555 X,Y,Z¡€remark 290: 2555 -X,-Y,Z¡€remark 290: 3555 -X,Y,-Z¡€remark 290: 4555 X,-Y,-Z¡€remark 290: 5555 Z,X,Y¡€remark 290: 6555 Z,-X,-Y¡€remark 290: 7555 -Z,-X,Y¡€remark 290: 8555 -Z,X,-Y¡€remark 290: 9555 Y,Z,X¡€remark 290: 10555 -Y,Z,-X¡€remark 290: 11555 Y,-Z,-X¡€remark 290: 12555 -Y,-Z,X¡€remark 290: 13555 Y,X,-Z¡€remark 290: 14555 -Y,-X,-Z¡€remark 290: 15555 Y,-X,Z¡€remark 290: 16555 -Y,X,Z¡€remark 290: 17555 X,Z,-Y¡€remark 290: 18555 -X,Z,Y¡€remark 290: 19555 -X,-Z,-Y¡€remark 290: 20555 X,-Z,Y¡€remark 290: 21555 Z,Y,-X¡€remark 290: 22555 Z,-Y,X¡€remark 290: 23555 -Z,Y,X¡€remark 290: 24555 -Z,-Y,-X¡€"remark 290: 25555 12+X,12+Y,12+Z¡€"remark 290: 26555 12-X,12-Y,12+Z¡€"remark 290: 27555 12-X,12+Y,12-Z¡€"remark 290: 28555 12+X,12-Y,12-Z¡€"remark 290: 29555 12+Z,12+X,12+Y¡€"remark 290: 30555 12+Z,12-X,12-Y¡€"remark 290: 31555 12-Z,12-X,12+Y¡€"remark 290: 32555 12-Z,12+X,12-Y¡€"remark 290: 33555 12+Y,12+Z,12+X¡€"remark 290: 34555 12-Y,12+Z,12-X¡€"remark 290: 35555 12+Y,12-Z,12-X¡€"remark 290: 36555 12-Y,12-Z,12+X¡€"remark 290: 37555 12+Y,12+X,12-Z¡€"remark 290: 38555 12-Y,12-X,12-Z¡€"remark 290: 39555 12+Y,12-X,12+Z¡€"remark 290: 40555 12-Y,12+X,12+Z¡€"remark 290: 41555 12+X,12+Z,12-Y¡€"remark 290: 42555 12-X,12+Z,12+Y¡€"remark 290: 43555 12-X,12-Z,12-Y¡€"remark 290: 44555 12+X,12-Z,12+Y¡€"remark 290: 45555 12+Z,12+Y,12-X¡€"remark 290: 46555 12+Z,12-Y,12+X¡€"remark 290: 47555 12-Z,12+Y,12+X¡€"remark 290: 48555 12-Z,12-Y,12-X¡€(remark 290: Where Nnn -> Operator Number¡€%remark 290: Mmm -> Translation Vector¡€5remark 290: Crystallographic Symmetry Transformations¡€Cremark 290: The Following Transformations Operate On The AtomHETATM¡€Aremark 290: Records In This Entry To Produce Crystallographically¡€remark 290: Related Molecules.¡€Cremark 290: Smtry1 1 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 1 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 1 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry1 2 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 2 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 2 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry1 3 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 3 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 3 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry1 4 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 4 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 4 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry1 5 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry2 5 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 5 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 6 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry2 6 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 6 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 7 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry2 7 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 7 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 8 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry2 8 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 8 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 9 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 9 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry3 9 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 10 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 10 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry3 10 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 11 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 11 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry3 11 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 12 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 12 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry3 12 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 13 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 13 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 13 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry1 14 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 14 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 14 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry1 15 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 15 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 15 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry1 16 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry2 16 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry3 16 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry1 17 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 17 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry3 17 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 18 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 18 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry3 18 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 19 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 19 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry3 19 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 20 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry2 20 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry3 20 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry1 21 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry2 21 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 21 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 22 0.000000 0.000000 1.000000 0.00000¡€Cremark 290: Smtry2 22 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 22 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 23 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry2 23 0.000000 1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 23 1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 24 0.000000 0.000000 -1.000000 0.00000¡€Cremark 290: Smtry2 24 0.000000 -1.000000 0.000000 0.00000¡€Cremark 290: Smtry3 24 -1.000000 0.000000 0.000000 0.00000¡€Cremark 290: Smtry1 25 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 25 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 25 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry1 26 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 26 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 26 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry1 27 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 27 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 27 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry1 28 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 28 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 28 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry1 29 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry2 29 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 29 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 30 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry2 30 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 30 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 31 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry2 31 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 31 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 32 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry2 32 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 32 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 33 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 33 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry3 33 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry1 34 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 34 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry3 34 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry1 35 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 35 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry3 35 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry1 36 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 36 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry3 36 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry1 37 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 37 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 37 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry1 38 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 38 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 38 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry1 39 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 39 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 39 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry1 40 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry2 40 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry3 40 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry1 41 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 41 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry3 41 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 42 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 42 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry3 42 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 43 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 43 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry3 43 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 44 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry2 44 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry3 44 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry1 45 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry2 45 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 45 -1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry1 46 0.000000 0.000000 1.000000 90.51500¡€Cremark 290: Smtry2 46 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 46 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry1 47 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry2 47 0.000000 1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 47 1.000000 0.000000 0.000000 90.51500¡€Cremark 290: Smtry1 48 0.000000 0.000000 -1.000000 90.51500¡€Cremark 290: Smtry2 48 0.000000 -1.000000 0.000000 90.51500¡€Cremark 290: Smtry3 48 -1.000000 0.000000 0.000000 90.51500¡€remark 290: Remark: Null¡€remark 300: Biomolecule: 1¡€Dremark 300: This Entry Contains The Crystallographic Asymmetric Unit¡€remark 500: Than 6Rmsd (Mmodel Number; Resresidue Name; Cchain¡€>remark 500: Identifier; Sseqsequence Number; Iinsertion Code).¡€remark 500: Standard Table:¡€?remark 500: Format: (10x,I3,1x,2(A3,1x,A1,I4,A1,1x,A4,3x),F6.3)¡€1remark 500: Expected Values: Engh And Huber, 1991¡€;remark 500: M Res Csseqi Atm1 Res Csseqi Atm2 Deviation¡€6remark 500: Met A 310 Ce Met A 310 Sd -0.080¡€6remark 500: Ile A 443 Cb Ile A 443 Ca 0.063¡€6remark 500: Met A 446 Ce Met A 446 Sd -0.072¡€(remark 500: Geometry And Stereochemistry¡€*remark 500: Subtopic: Covalent Bond Angles¡€Cremark 500: The Stereochemical Parameters Of The Following Residues¡€Bremark 500: Have Values Which Deviate From Expected Values By More¡€>remark 500: Than 6Rmsd (Mmodel Number; Resresidue Name; Cchain¡€>remark 500: Identifier; Sseqsequence Number; Iinsertion Code).¡€remark 500: Standard Table:¡€Cremark 500: Format: (10x,I3,1x,A3,1x,A1,I4,A1,3(1x,A4,2x),12x,F5.1)¡€1remark 500: Expected Values: Engh And Huber, 1991¡€+remark 500: M Res Csseqi Atm1 Atm2 Atm3¡€Bremark 500: Asp A 125 N - Ca - C Angl. Dev. -12.9 Degrees¡€Bremark 500: Gln A 226 N - Ca - C Angl. Dev. 12.1 Degrees¡€Bremark 500: Asn A 299 N - Ca - C Angl. Dev. -11.7 Degrees¡€Bremark 500: Thr A 323 N - Ca - C Angl. Dev. 10.2 Degrees¡€remark 525: Solvent¡€Eremark 525: The Following Solvent Molecules Lie Farther Than Expected¡€@remark 525: From The Protein Or Nucleic Acid Molecule And May Be¡€?remark 525: Associated With A Symmetry Related Molecule (Mmodel¡€Dremark 525: Number; Resresidue Name; Cchain Identifier; Sseqsequence¡€%remark 525: Number; Iinsertion Code):¡€remark 525: M Res Csseqi¡€8remark 525: 0 Hoh 9119 Distance 6.47 Angstroms¡€remark 900: Related Entries¡€.remark 900: Related Id: 7nn9 Related Db: Pdb¡€Fremark 900: Three-Dimensional Structure Of The Complex Of 4-Guanidino-¡€?remark 900: Neu5ac2en And Influenza Virus Neuraminidase Protein¡€Gremark 900: Science(1995),4:1081-1087 J.N.Varghese, V.C.Epa, P.M.Colman¡€.remark 900: Related Id: 1f8c Related Db: Pdb¡€.remark 900: Related Id: 1f8d Related Db: Pdb¡€.remark 900: Related Id: 1f8e Related Db: Pdb¡€CDbref 1f8b A 82 468 Gb 324880 Aaa43574 83 470¡€9Seqadv 1f8b Met A 376 Gb 324880 Ile 377 Conflict¡€9Seqadv 1f8b Asp A 386 Gb 324880 Glu 387 Conflict¡€9Seqadv 1f8b Lys A 387 Gb 324880 Arg 388 Conflict¡€/Modres 1f8b Asn A 86 Asn Glycosylation Site¡€/Modres 1f8b Asn A 200 Asn Glycosylation Site¡€/Modres 1f8b Asn A 146 Asn Glycosylation Site¡€8Link O4 Nag X 202 C1 Man X 203¡€8Link O2 Man X 205 C1 Man X 206¡€8Link O3 Man X 203 C1 Man X 204¡€8Link C1 Man X 207 O6 Man X 203¡€8Link C1 Nag X 202 O4 Nag X 201¡€8Link Nd2 Asn A 86 C1 Nag Y 86¡€8Link C1 Man X 205 O2 Man X 204¡€8Link C1 Nag X 201 Nd2 Asn A 200¡€8Link Nd2 Asn A 146 C1 Nag A1146¡€;Cispep 1 Asn A 325 Pro A 326 0 -0.58¡€;Cispep 2 Arg A 430 Pro A 431 0 0.43£€0€¢€0€ €Protein Data Bank¡€ €¡€0€ €Ñ¡€¢€ ¢€¡€0€ €PDB¡€¡€1F8B£€¡€0€ €С€¢€¤€¡€0€ €0€ € €0€0€ €¡€0€ €Smith£€ B.J.Smith¤€B.J.0€ €¡€0€ €Colman£€ P.M.Colman¤€P.M.0€ €¡€0€ € Von Itzstein£€M.Von Itzstein¤€M.0€ €¡€0€ €Danylec£€ B.Danylec¤€B.0€ €¡€0€ €Varghese£€ J.N.Varghese¤€J.N.¡€0€ €¡€0€ €С€¢€¤€«€1€¤€0€ €1€ €?Analysis of inhibitor binding in influenza virus neuraminidase.¡€0€ € €0€0€ €¡€0€ €Smith¤€B.J.0€ €¡€0€ €Colman¤€P.M.0€ €¡€0€ € Von Itzstein¤€M.0€ €¡€0€ €Danylec¤€B.0€ €¡€0€ €Varghese¤€J.N.¡€ €`Biomolecular Research Institute, Parkville, Victoria 3052, Australia. brian.smith@bioresi.com.au¢€ €0€ €1€¤€ Protein Sci.¥€ Protein Sci§€ 0961-8368£€BNW¡€0€ €¡€0€ €Ñ¡€¡€10¢€4£€689-696¨€eng£€1€ €¬Û¡€C¿£€C¿¢€0€ €0€ €>Native Influenza Virus Neuraminidase In Complex With Neu5ac2en¡€HydrolaseHYDROLASE INHIBITOR¢€âMol_id: 1; Organism_scientific: Influenza A Virus; Organism_common: Virus; Strain: ATERNAUSTRALIAG70C75; Expression_system: Influenza A Virus; Expression_system_common: Virus; Expression_system_strain: Recombinant (NwsG70C) N9£€‚BNative Influenza Virus Neuraminidase In Complex With Neu5ac2en Neuraminidase, Hydrolase, Influenza Protein, Glycosylated Protein, Dana Mol_id: 1; Molecule: Neuraminidase; Chain: A; Fragment: Integral Membrane Protein, Membrane Stalk Cleaved By Pronase Releasing Fully Active Residues 82-468.; Ec: 3.2.1.18; Engineered: Yes§€ÿ¡€0€0€ €¡€0€ €A£€SEQRES¨€¥€0€¢€0€ €Influenza A virus£€1€0€ €taxon¡€ €,8¥€0€ €¤€0€0€ €¡€genus¢€Influenza A virus£€lViruses; ssRNA negative-strand viruses; Orthomyxoviridae; Influenza virus A and B group; Influenza A viruses¤€¦€VRL¢€«€Ùß壀0€0€ €¡€ 82 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 83 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ €¡€ 84 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€(0€ €¡€ 85 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 86 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 87 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ €¡€ 88 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ €¡€ 89 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€"0€ € ¡€ 90 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 91 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€0€ € ¡€ 92 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€ 0€ € ¡€ 93 ¢€¢€0€ €¡€0€ €Standard residue dictionary¡€ €¡€10€ € ¡€ 94 ¢€¢€0€ €¡€0€ €Standard residue 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